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Unsupervised PrEP in routine practice: a new challenge?

Hélène Laroche 1 Caroline Lions 1 Olivia Zaegel-Faucher 1 Catherine Tamalet 2 Isabelle Poizot-Martin 1, 3
1 Service d'Immuno-hématologie clinique [Hôpital Sainte Marguerite - APHM]
2 IHU Méditerranée Infection - Pôle des Maladies Infectieuses et Tropicales Clinique et Biologique [Hôpital de la Timone - APHM]
3 SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale
Abstract : Pre-exposure prophylaxis (PrEP) for the prevention of HIV infection with 300 mg daily tenofovir co-formulated with 200 mg emtricitabine is recommended as one prevention option for people who are at substantial risk of acquiring an HIV infection. We report the case of a 28-year-old man who has sex with men and who was referred to our unit for a primary HIV infection with positive p18, p24 and gp160 bands on Western blot analysis but with a low HIV plasma viral load. Although HIV misdiagnosis should always be considered in cases of atypical seroconversion pattern with a low viral burden, unsupervised PrEP should be systematically investigated.
Keywords : Prevention human immunodeficiency virus sexual behaviour diagnosis treatment
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Journal articles
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https://hal-amu.archives-ouvertes.fr/hal-02613510
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Submitted on : Wednesday, May 20, 2020 - 10:56:11 AM
Last modification on : Wednesday, August 19, 2020 - 12:08:18 PM

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UNIV-AMU | U1252 | INSERM

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Hélène Laroche, Caroline Lions, Olivia Zaegel-Faucher, Catherine Tamalet, Isabelle Poizot-Martin. Unsupervised PrEP in routine practice: a new challenge?. International Journal of STD and AIDS, SAGE Publications, 2019, 30 (7), pp.715-717. ⟨10.1177/0956462419828872⟩. ⟨hal-02613510⟩

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