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Excito-repellency and biological safety of β-caryophyllene oxide against Aedes albopictus and Anopheles dirus (Diptera: Culicidae)

Abstract :  β-caryophyllene oxide had stronger repellent and irritant effect than DEET  Ae. albopictus was more sensitive to β-caryophyllene oxide than An. dirus while, knockdown responses (37%) were observed in An. dirus exposed to 1% β-caryophyllene oxide in the contact trial.  β-caryophyllene oxide did not show any phototoxic activity.  None of the tested β-caryophyllene oxide induced a significant increase of micronucleated cells with or without metabolic activation.  β-Caryophyllene oxide could be considered as a safe repellent, effective against mosquitoes.
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https://hal-amu.archives-ouvertes.fr/hal-02941392
Contributor : Stéphane Greff <>
Submitted on : Tuesday, December 8, 2020 - 1:42:13 PM
Last modification on : Wednesday, December 9, 2020 - 3:39:09 AM

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Jirod Nararak, Carole Di Giorgio, Chutipong Sukkanon, Valerie Mahiou-Leddet, Evelyne Ollivier, et al.. Excito-repellency and biological safety of β-caryophyllene oxide against Aedes albopictus and Anopheles dirus (Diptera: Culicidae). Acta Tropica, Elsevier, 2020, 210, pp.105556. ⟨10.1016/j.actatropica.2020.105556⟩. ⟨hal-02941392⟩

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