Differential DNA methylation analysis across the promoter regions using methylated DNA immunoprecipitation sequencing profiling of porcine loin muscle

Kaj Chokeshaiusaha (1) , Denis Puthier (2) , Thanida Sananmuang (1) , Em-On Olanratmanee (1) , Catherine Nguyen (2) , Roongtham Kedkovid (3)

1 RMUTT - Rajamangala University of Technology Thanyaburi
2 TAGC - Theories and Approaches of Genomic Complexity
3 Chulalongkorn University [Bangkok]

Pork leanness and marbling are among the essential traits of consumer preference. To acquire knowledge about universal epigenetic regulations for improving breed selection, a meta-analysis of methylated DNA immunoprecipitation sequencing (MeDIP-seq) profiling data of mixed loin muscle types was performed in this study.

Keywords: differential DNA methylation; lean; loin muscle; marbled; methylated DNA immunoprecipitation sequencing; transcription start site

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Genomics [q-bio.GN]; Computer Science [cs]; Bioinformatics [q-bio.QM]

Kaj Chokeshaiusaha, Denis Puthier, Thanida Sananmuang, Em-On Olanratmanee, Catherine Nguyen, et al.. Differential DNA methylation analysis across the promoter regions using methylated DNA immunoprecipitation sequencing profiling of porcine loin muscle. Veterinary World, 2020, 13, pp.1113 - 1125. ⟨10.14202/vetworld.2020.1113-1125⟩. ⟨hal-03015708⟩