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Mind the gap: from neurons to networks to outcomes in multiple sclerosis

Declan Chard 1, 2 Adnan Alahmadi 3 Bertrand Audoin 4, 5, 6 Thalis Charalambous 1 Christian Enzinger 7, 8 Hanneke Hulst 9 Maria Rocca 10 Àlex Rovira 11 Jaume Sastre-Garriga 12 Menno Schoonheim 9 Betty Tijms 13 Carmen Tur 1, 14 Claudia Gandini Wheeler-Kingshott 1, 15, 16 Alle Meije Wink 17 Olga Ciccarelli 1, 2 Frederik Barkhof 2, 17, 18
1 NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, Faculty of Brain Sciences, University College London, London
2 National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre, London
3 Department of Diagnostic Radiology, Faculty of Applied Medical Science, King Abdulaziz University (KAU), Jeddah
4 CRMBM - Centre de résonance magnétique biologique et médicale
5 CEMEREM - Centre d'Exploration Métabolique par Résonance Magnétique [Hôpital de la Timone - AP-HM]
6 AP-HM, CHU Timone, Pole de Neurosciences Cliniques, Department of Neurology, Marseille, France.
7 Department of Neurology, Research Unit for Neuronal Repair and Plasticity, Medical University of Graz, Graz
8 Department of Radiology, Division of Neuroradiology, Vascular and Interventional Radiology, Medical University of Graz, Graz
9 Department of Anatomy and Neurosciences, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam
10 Neuroimaging Research Unit and Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan
11 Section of Neuroradiology, Department of Radiology Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona
12 Servei de Neurologia/Neuroimmunologia, Multiple Sclerosis Centre of Catalonia (Cemcat), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona
13 Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam
14 Department of Neurology, Luton and Dunstable University Hospital, Luton
15 Department of Brain and Behavioural Sciences, University of Pavia, Pavia
16 Brain MRI 3T Research Center, IRCCS Mondino Foundation, Pavia
17 Department of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam
18 Institutes of Neurology and Healthcare Engineering, University College London, London
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Submitted on : Thursday, December 23, 2021 - 10:54:31 AM
Last modification on : Tuesday, January 4, 2022 - 5:58:24 AM

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Declan Chard, Adnan Alahmadi, Bertrand Audoin, Thalis Charalambous, Christian Enzinger, et al.. Mind the gap: from neurons to networks to outcomes in multiple sclerosis. Nature Reviews Neurology, Nature Publishing Group, 2021, 17 (3), pp.173-184. ⟨10.1038/s41582-020-00439-8⟩. ⟨hal-03501361⟩

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