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Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3 + CD8 + T regs

Thorsten Joeris 1, 2 Cristina Gomez-Casado 2 Petra Holmkvist 2 Simon Tavernier 3, 4 Aaron Silva-Sanchez 5 Luisa Klotz 6 Troy Randall 7 Allan Mowat 8 Knut Kotarsky 2 Bernard Malissen 9 William Agace 2, 1 
1 Department of Health Technology, Technical University of Denmark
DTU - Danmarks Tekniske Universitet = Technical University of Denmark
2 Lund University [Lund]
3 Ghent University Hospital
4 IRC - VIB-UGent Center for Inflammation Research [Gand, Belgique]
5 University of Alabama at Birmingham, department od Medicine
6 UKM - University Hospital Münster - Universitaetsklinikum Muenster [Germany]
7 University of Alabama at Birmingham - Department of Medicine
8 University of Glasgow - Institute of Infection, Immunity and Inflammation
9 CIML - Centre d'Immunologie de Marseille - Luminy
Abstract : Intestinal cDC1 drive the generation of FoxP3 + CD8 + T regs to maintain tolerance to epithelial-derived self-antigen.
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https://hal-amu.archives-ouvertes.fr/hal-03565973
Contributor : Anita DUMENIL Connect in order to contact the contributor
Submitted on : Friday, February 11, 2022 - 12:06:32 PM
Last modification on : Friday, August 5, 2022 - 12:36:13 PM

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Thorsten Joeris, Cristina Gomez-Casado, Petra Holmkvist, Simon Tavernier, Aaron Silva-Sanchez, et al.. Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3 + CD8 + T regs. Science Immunology, 2021, 6 (60), ⟨10.1126/sciimmunol.abd3774⟩. ⟨hal-03565973⟩

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