The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair

Jack Mccowan (1, 1) , Frédéric Fercoq (2) , Phoebe Kirkwood (1, 1) , Wouter T’jonck (1, 1) , Lizi Hegarty (1, 1) , Connar Mawer (1) , Richard Cunningham (1, 1) , Ananda Mirchandani (1, 1) , Anna Hoy (1, 1) , Duncan Humphries (1, 1) , Gareth-Rhys Jones (1, 1) , Carsten Hansen (1, 1) , Nik Hirani (1, 1) , Stephen Jenkins (1, 1) , Sandrine Henri (3) , Bernard Malissen (3, 4) , Sarah Walmsley (1, 1) , David Dockrell (1, 1) , Philippa Saunders (1, 1) , Leo Carlin (2, 5) , Calum Bain (1, 1)

1 Edin. - University of Edinburgh
2 Cancer Research UK Beatson Institute [Glasgow]
3 CIML - Centre d'Immunologie de Marseille - Luminy
4 CIPHE - Centre d'Immunophénomique
5 Institute of Cancer Sciences, University of Glasgow

EGR2 controls alveolar macrophage function in health and disease.

Domaines: Sciences du Vivant [q-bio]

Jack Mccowan, Frédéric Fercoq, Phoebe Kirkwood, Wouter T’jonck, Lizi Hegarty, et al.. The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair. Science Immunology, 2021, 6 (65), ⟨10.1126/sciimmunol.abj2132⟩. ⟨hal-03666009⟩