Steroidal lactams: A review
Résumé
Steroidal lactams are also a class of steroid derivatives that were synthesized and modified to increase the biological activity of steroids. Their synthesis is a stimulating challenge to the scientist, often claiming the development of new and generally useful reactions. Some of them have been tested successfully as anticancer drugs against different types of leukemia. Recent developments in the syntheses of steroidal lactams are described herein. The biological activities of those steroidal derivatives for which data are available are given.
Domaines
Chimie organique
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