Expeditious Synthesis of the Cores of Naturally Occurring Cyclic Polyethers using a Divergent Ring Rearrangement Metathesis Strategy

Philippe Escavabaja (1) , Jacques Viala (1) , Yoann Coquerel (1) , Jean Rodriguez (1)

1 STeRéO

Ring rearrangement metathesis (RRM) strategies are proposed for the expeditious synthesis of the cores of naturally occurring cyclic polyethers of the dysiherbaine and acetogenin families, as well as a hybrid compound, from 8-oxabicyclo- [3.2.1]octenes.

Mots clés: homogeneous catalysis; metathesis; natural products; rearrangement; synthetic methods

Domaines: Chimie organique

Philippe Escavabaja, Jacques Viala, Yoann Coquerel, Jean Rodriguez. Expeditious Synthesis of the Cores of Naturally Occurring Cyclic Polyethers using a Divergent Ring Rearrangement Metathesis Strategy. Advanced Synthesis and Catalysis, 2012, 354, pp.3200-3204. ⟨10.1002/adsc.201200665⟩. ⟨hal-00801885⟩