Determining carbon-carbon connectivities in natural abundance organic powders using dipolar couplings

Myriam Dekhil (1) , Giulia Mollica (1) , Tristan Texier Bonniot (1) , Fabio Ziarelli (2) , Pierre Thureau (1) , Stéphane Viel (3, 1)

1 ICR - Institut de Chimie Radicalaire
2 AMU SPEC - Spectropôle - Aix Marseille Université
3 IUF - Institut universitaire de France

We present a solid-state NMR methodology capable of investigating the carbon skeleton of natural abundance organic powders. The methodology is based on the C-13-C-13 dipolar coupling interaction and allows carbon-carbon connectivities to be unambiguously established for a wide range of organic solids. This methodology is particularly suitable for disordered solids, such as natural or synthetic macromolecules, which cannot be studied using conventional diffraction or NMR techniques.

Mots clés: C-13-C-13 correlation; correlation spectroscopy; crystal-structure; disordered solids; isotopic abundance; mas nmr; nuclear-magnetic-resonance; pulse sequence; rotating solids; solid-state nmr

Domaines: Chimie analytique; Chimie organique

Myriam Dekhil, Giulia Mollica, Tristan Texier Bonniot, Fabio Ziarelli, Pierre Thureau, et al.. Determining carbon-carbon connectivities in natural abundance organic powders using dipolar couplings. Chemical Communications, 2016, 52 (55), pp.8565--8568. ⟨10.1039/c6cc04202c⟩. ⟨hal-01460667⟩