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Role of glyphosate in the emergence of antimicrobial resistance in bacteria?

Didier Raoult 1 Linda Hadjadj 1 Sophie Alexandra Baron 1 Jean-Marc Rolain 1 
1 MEPHI - Microbes évolution phylogénie et infections
Abstract : There is a discrepancy between antibiotic use in medicine and agriculture in the intertropical zone and frequency of antibiotic resistance in clinical bacteria in these countries. We provide evidence that glyphosate (a herbicide but also an antibiotic drug) could be a possible driver of antibiotic resistance in countries where this herbicide is widely used because of modification of the microbial environment. Emergence of resistance in bacteria and fungi is correlated with glyphosate use in the world over the last 40 years.
Keywords : antibiotics antibiotic resistance bacterial agriculture drug resistance microbial herbicides bacteria fungus glyphosate multi-antibiotic resistance
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Submitted on : Friday, September 17, 2021 - 3:46:29 PM
Last modification on : Friday, April 1, 2022 - 3:44:08 AM
Long-term archiving on: : Saturday, December 18, 2021 - 7:00:53 PM

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Didier Raoult, Linda Hadjadj, Sophie Alexandra Baron, Jean-Marc Rolain. Role of glyphosate in the emergence of antimicrobial resistance in bacteria?. Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2021, 76 (7), pp.1655-1657. ⟨10.1093/jac/dkab102⟩. ⟨hal-03334121⟩

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