Autoclave Sterilization of PEDOT:PSS Electrophysiology Devices

Ilke Uguz (1) , Mehran Ganji (2) , Adel Hama (1) , Atsunori Tanaka (2) , Sahika M Inal (1) , Ahmed A Youssef (2) , Roisin M Owens (1) , Pascale P Quilichini (3) , Antoine Ghestem (3) , Christophe Bernard (3) , Shadi A Dayeh (2) , George G Malliaras (1)

1 EMSE-CMP
2 ECE - UC San Diego - Department of Electrical and Computer Engineering [Univ California San Diego]
3 INS - Institut de Neurosciences des Systèmes

Autoclaving, the most widely available sterilization method, is applied to poly(3,4ethylenedioxythiophene) doped with polystyrene sulfonate (PEDOT:PSS) electrophysiology devices. The process does not harm morphology or electrical properties, while it effectively kills E. coli intentionally cultured on the devices. This finding paves the way to widespread introduction of PEDOT:PSS electrophysiology devices to the clinic.

Domains: Neurons and Cognition [q-bio.NC]; Engineering Sciences [physics]

Ilke Uguz, Mehran Ganji, Adel Hama, Atsunori Tanaka, Sahika M Inal, et al.. Autoclave Sterilization of PEDOT:PSS Electrophysiology Devices. Advanced Healthcare Materials, 2016, 5, pp.3094 - 3098. ⟨10.1002/adhm.201600870⟩. ⟨hal-03796152⟩